Abstract
We found alpha-glucosidase inhibitory effect of Zn(II) complex with 6-methyl-2-picolinmethylamide (6mpa-ma) which showed the highest blood glucose lowering effect in Zn(II) complexes with picolinamide derivatives in KK-A y mice. The Zn(II) complex showed strong alpha-glucosidase inhibitory activity greater by about eighty times (substrate: maltose) and forty times (substrate: sucrose) compared with acarbose. © 2005 Pharmaceutical Society of Japan.
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Ueda, E., Yoshikawa, Y., Sakurai, H., Kojima, Y., & Kajiwara, N. M. (2005). In vitro alpha-glucosidase inhibitory effect of Zn(II) complex with 6-methyl-2-picolinmethylamide. Chemical and Pharmaceutical Bulletin, 53(4), 451–452. https://doi.org/10.1248/cpb.53.451
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