Special proresolving mediators (SPMs) limit the intensity of inflammation; however, their regulation is poorly understood. In this issue of Immunity, Li etal. (2013) describe bipolar roles for miR-466l in the promotion of inflammation and the induction of SPMs. © 2013 Elsevier Inc.
Ward, P. A. (2013, November 14). The bipolar role of miR-466l in inflammation. Immunity. Cell Press. https://doi.org/10.1016/j.immuni.2013.10.014