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Effect of repeat-sprint training in hypoxia on post-exercise interleukin-6 and F2-isoprostanes

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Abstract

This investigation examined the oxidative stress (F2-Isoprostane; F2-IsoP) and inflammatory (interleukin-6; IL-6) responses to repeat-sprint training in hypoxia (RSH). Ten trained male team sport athletes performed 3(sets)*9(repetitions)*5 s cycling sprints in simulated altitude (3000 m) and sea-level conditions. Mean and peak sprint power output (MPO and PPO) were recorded, and blood samples were collected pre-exercise, and again at 8 and 60 min post-exercise. Both MPO and PPO were significantly reduced in hypoxia (compared to sea-level) in the second (MPO: 855 ± 89 vs. 739 ± 95 W, p =.006; PPO: 1024 ± 114 vs. 895 ± 112 W, p =.010) and third (MPO: 819 ± 105 vs. 686 ± 83 W, p =.008; PPO: 985 ± 125 vs. 834 ± 99 W, p =.008) sets, respectively. IL-6 was significantly increased from pre- to 1 h post-exercise in both hypoxia (0.7 ± 0.2 vs. 2.4 ± 1.4 pg/mL, p =.004) and sea-level conditions (0.7 ± 0.2 vs. 1.6 ± 0.3 pg/mL, p

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Goods, P. S. R., Dawson, B., Landers, G. J., Gore, C. J., Croft, K., & Peeling, P. (2016). Effect of repeat-sprint training in hypoxia on post-exercise interleukin-6 and F2-isoprostanes. European Journal of Sport Science, 16(8), 1047–1054. https://doi.org/10.1080/17461391.2015.1123776

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