Transcriptional regulation and its misregulation in disease

435Citations
Citations of this article
1.5kReaders
Mendeley users who have this article in their library.

Abstract

The gene expression programs that establish and maintain specific cell states in humans are controlled by thousands of transcription factors, cofactors, and chromatin regulators. Misregulation of these gene expression programs can cause a broad range of diseases. Here, we review recent advances in our understanding of transcriptional regulation and discuss how these have provided new insights into transcriptional misregulation in disease. © 2013 Elsevier Inc.

Cite

CITATION STYLE

APA

Lee, T. I., & Young, R. A. (2013, March 14). Transcriptional regulation and its misregulation in disease. Cell. https://doi.org/10.1016/j.cell.2013.02.014

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free