The Effect of Degradation Time Variation on Porous Magnesium Implant Bone Scaffold

Abstract

This paper proposes a modeling approach for biodegradation of implant-bone scaffolds. A Computer simulation was performed to determine the wall shear stress (WSS) and permeability of simulated body fluid (SBF) with a constant flow rate of 0.025 ml/min. In this study, four morphological samples were used to immersion time from 0 to 72 hours. Each specimen was given a different bone strain (1000-3500 μstrain) which created a variation of displacement in the bone scaffold. The method used in the simulation was the fluid-structure interaction (FSI). The pressure drop through the specimen decreases linearly, the permeability increases as the porosity increases, and the mean wall shear stress decreases due to the length of the immersion time. It was obtained that the permeability values of the implant-bone scaffold increases from 7.79×10-10 m 2 to 1.09×10-9 m 2 and the mean shear stress values decrease from 2.86×10 -3 Pa to 1.38×10 -3 Pa.