Effect of a carbonic anhydrase inhibitor (Diamox) on intra-ocular pressure of rabbits and cats

Abstract

Intravenous injections of sodium Diamox in doses of 5 and 50 mg./kg. reduced the normal intra-ocular pressure in anaesthetized rabbits and cats. Subconjunctival injections, intra-carotid injections, and injections into the anterior chamber did not reduce the intra-ocular pressure. Blood-flow estimations showed that sodium Diamox can cause a transient vasodilatation.