High serum concentrations of dimeric inhibins A and B in normal newborn girls

11Citations
Citations of this article
8Readers
Mendeley users who have this article in their library.

Abstract

Objective: To establish the serum pattern of dimeric inhibins in normal girls during the newborn period and to examine its relationship with the postnatal gonadotropic surge. Design: Retrospective study. Setting: Division of endocrinology of a children's hospital. Patient(s): Thirty-one girls 4 to 65 days of age. Main Outcome Measure(s): Serum levels of FSH, LH, and inhibin A and B. Result(s): High serum concentrations of both dimeric inhibins were detected during the first weeks of life. Concentrations tended to decrease through the second month of age. Inhibin A and B concentrations positively correlated with age only during the first 2 weeks of life (r = .57, P<.05 and r = .70, P<.01, respectively). Inhibin A and B were positively and significantly correlated with LH (r = .57, P<.05 and r = .52, P<.05, respectively) and with each other (r = .68, P<.0001). No correlation was found between dimeric inhibins and FSH. Conclusion(s): The high inhibin concentrations observed in newborn girls, which indicate advanced follicular development and granulosa cell differentiation, may be useful markers for congenital gonadal disorders. Copyright © 2002 American Society for Reproductive Medicine.

Author supplied keywords

Cite

CITATION STYLE

APA

Bergadá, I., Ballerini, G. M., Ayuso, S., Groome, N. P., Bergadá, C., & Campo, S. (2002). High serum concentrations of dimeric inhibins A and B in normal newborn girls. Fertility and Sterility, 77(2), 363–365. https://doi.org/10.1016/S0015-0282(01)02965-X

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free