Emerging technologies of polymeric nanoparticles in cancer drug delivery

0Citations
Citations of this article
115Readers
Mendeley users who have this article in their library.

Abstract

Polymeric nanomaterials have the potential to improve upon present chemotherapy delivery methods. They successfully reduce side effects while increasing dosage, increase residence time in the body, offer a sustained and tunable release, and have the ability to deliver multiple drugs in one carrier. However, traditional nanomaterial formulations have not produced highly therapeutic formulations to date due to their passive delivery methods and lack of rapid drug release at their intended site. In this paper, we have focused on a few smart technologies that further enhance the benefits of typical nanomaterials. Temperature and pH-responsive drug delivery devices were reviewed as methods for triggering release of encapsulating drugs, while aptamer and ligand conjugation were discussed as methods for targeted and intracellular delivery, with emphases on in vitro and in vivo works for each method.

Cite

CITATION STYLE

APA

Brewer, E., Coleman, J., & Lowman, A. (2011). Emerging technologies of polymeric nanoparticles in cancer drug delivery. Journal of Nanomaterials. https://doi.org/10.1155/2011/408675

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free