The steady-state formation of prooxidants in cells and organs is balanced by a similar rate of their consumption by antioxidants that are enzymatic and/or nonenzymatic. "Oxidative stress" results from imbalance in this prooxidantantioxidant equilibrium in favor of the prooxidants. A number of diseases are associated with oxidative stress, being the basis of a potential antioxidant therapy. However, current evidence in clinical research does not show unequivocal distinction between causal or associative relationships of prooxidants to the disease process. © 1991 Springer-Verlag.
CITATION STYLE
Sies, H. (1991). Role of reactive oxygen species in biological processes. Klinische Wochenschrift, 69(21–23), 965–968. https://doi.org/10.1007/BF01645140
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