Perinatal morbidity and mortality of children born to mothers with chronic kidney disease

Abstract

Introduction: Chronic kidney disease (CKD) associated with pregnancy increases the risk of maternal and fetal complications. Objective: To determine perinatal morbidity and mortality of children born to mothers with mild and moderate CKD during pregnancy. Methods: Retrospective study of medical records of women with mild and moderate CKD during pregnancy cared for at La Raza National Medical Center between 2010 and 2016. Results: There were 142 patients, 99 (69.72 %) with mild CKD and 43 (30.28 %) with moderate CKD; 79 neonates (55.63 %) reached full term, 28 (19.71 %) had growth restriction; 44 (30.98 %), low birth weight and 54 (38.02 %) were admitted to the neonatal intensive care unit (NICU); four women (4.04 %) had an abortion; in four (2.81 %), their children had intrauterine death, and in 10 (7.04 %), neonatal death. High blood pressure (OR = 6.93) and hemoglobin < 11 g/dL (OR = 2.48) were risk factors for prematurity. Conclusion: A relationship was found between anemia and blood pressure levels and risk for prematurity, low Apgar and NICU admission.