Allele-specific PCR for determination of IL28B genotype

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Abstract

The IL28B genotype is a critical determinant of interferon response in patients infected with hepatitis C virus genotype 1. We describe an allele-specific PCR assay for the IL28B genotype. The assay is simple and robust, uses commonly available real-time PCR instrumentation, and is well suited for clinical laboratories offering IL28B genotyping. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

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Cook, L., Diem, K., Kim, W., Scott, J. D., & Jerome, K. R. (2012). Allele-specific PCR for determination of IL28B genotype. Journal of Clinical Microbiology, 50(12), 4144–4146. https://doi.org/10.1128/JCM.02084-12

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