Research progress of microrobots in tumor drug delivery

Abstract

With its cellular/subcellular size, microrobots expand a new vision for exploring drug delivery. It has unique advantages in achieving targeted delivery and precise recruitment of chemotherapy drugs. This paper reviews the relevant research at home and abroad in recent years. It searches the relevant literature in the past 10 years with the keywords “tumor drugs” and “micro-nano robots”. The results obtained were described according to “research progress of tumor therapeutic drugs”, “nano drug delivery system” and “microrobots drug delivery”. Then focused the main discussion on “microrobots and cancer drug delivery”. Through this research, its micro-size and multi-source drive provides microrobots technical basis. As the result, they can achieve in-vivo motion efficiency, targeted path planning, biological barrier penetration and efficient drug delivery. It might be beneficial for microrobots to earn better therapeutic of tumor drugs, while decreasing side-effects to other tissues and organs in the future.