A 29-year-old female took Niflec®, an oral electrolyte lavage solution, before surgery to remove angiomyolipoma on the right kidney. Thirty minutes later, erythematous macules and heat sensation developed over her whole body, followed by facial swelling and dyspnea. Her symptoms were resolved by fluid replacement and intravenous corticosteroid. Prick tests showed positive reactions to Niflec® and macrogol 4000, a constituent of Niflec®, as well as macrogol 400, 1500 and 6000. Based on these results, we diagnosed this case as having an anaphylactic response to macrogol 4000 contained in Niflec®.
Haneda, T., Natsuaki, M., & Yamanishi, K. (2011). A case of anaphylaxis to Niflec®. Skin Research, 10(3), 199–202. https://doi.org/10.11340/skinresearch.10.3_199