Screening for glucose-6-phosphate dehydrogenase deficiency in blood donors

10Citations
Citations of this article
9Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Aim: Our purpose was to determine the frequency of glucose-6-phosphate dehydrogenase (G6PD) deficiency in blood donors of Jahrom, Iran. Methods: Blood samples were obtained from the 706 blood donors who referred to Jahrom Blood Transfusion Organization between June and September 2008. Enzyme assays were performed three times, on day 1 (day of blood sampling), 7 and 45 days after blood storage. G6PD activity was measured using a quantitative assay. Results: A total of 706 samples were examined. 97•7% males and 2•3% females, mean age 32•6 years (18-64 years). Based on enzyme activity less than 1•62 IU/g hemoglobin (Hb), prevalence of G6PD deficiency in three separate measurements was 16•3, 19•1 and 33•3% respectively. Four percent of donor had an enzyme level of zero on day 1 which increased to 7•4 and 10•7% on the seventh and the forty-fifth days. Conclusion: The results of this study support the screening for G6PD as part of the routine workup of blood donors in areas with a high prevalence of G6PD deficiency. © 2010 W. S. Maney & Son Ltd.

Author supplied keywords

Cite

CITATION STYLE

APA

Emamghorashi, F., Hoshmand, F., & Mohtashamifar, A. (2010). Screening for glucose-6-phosphate dehydrogenase deficiency in blood donors. Hematology, 15(2), 122–124. https://doi.org/10.1179/102453310X12583347010179

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free