Eosinophilic ulcer of oral mucosa

Abstract

A 41-year-old woman was seen for the examination of a painless lesion on the posterior hard palate of 2 weeks' duration. She had no systemic symptoms. Examination of the hard palate showed a single 1 x 1 cm, round, punched out ulcer with an erythematous base; the margins of the ulcer were slightly raised and indurated (Fig. 1). Other clinical findings were normal and laboratory study of a cutaneous biopsy showed necrotic ulceration with dense inflammatory cell infiltration. An extensive inflammatory cell infiltration with predominantly eosinophilic cells was present throughout the submucosa. A single application of liquid nitrogen decreased the lesion.