Postural hemodynamic parameters in older persons have a seasonal dependency: A pilot study

Abstract

Aims: It is known that blood pressure regulation differs seasonally. It is unknown, however, how the cardiovascular system in patients with a stroke reacts to postural changes in different seasons. The aim was therefore to investigate how different temperatures in cold and warm seasons influence the reactions of haemodynamic mechanisms as well as heart rate variability during a sit-to-stand test in patients with stroke and a control group. Methods: Hemodynamic responses were assessed in both groups during a sit-to-stand test (5 min sitting followed by 5 min standing) beat to beat within two different seasons. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP), heart rate (HR), stroke index (SI), cardiac index (CI) and heart rate variability (HRV) were continuously monitored. Results: During the sitting baseline period delta values of DBP (+15.1 [Standard error (SE) 3.75] mmHg, p < 0.05) and MBP (+14.35 [SE 4.18] mmHg, p < 0.05) were significantly higher in colder months compared to warmer months whereas SI (−3.86 [SE 1.43] ml/beat/m2, p < 0.05) and CI (−0.4 [SE 0.11] l/min/m2, p < 0.05) were lower in colder months compared to warmer months in non-stroke participants. In patients with stroke during sitting, baseline period delta values of DBP (+19.92 [SE 8.03] mmHg, p < 0.05) and MBP (+19.29 [SE 8.6] mmHg, p < 0.05) were significantly higher in colder months compared to warmer months but SI (−5.43 [SE 1.96] ml/beat/m2, p < 0.05) was significantly lower in colder months compared to warmer months. After standing, there was a significant decrease in SBP in warmer months (−16.84 [SE 4.38] mmHg, p < 0.05) and a decrease in DBP in warmer months (−7.8 [SE 2.3] mmHg, p < 0.05) and colder months (−6.73 [SE 1.5] mmHg, p < 0.05) in non-stroke participants and a decrease in MBP in warmer months (−12.5 [SE 2.8] mmHg, p < 0.05) and colder months (−8.93 [SE 1.8] mmHg, p < 0.05) in non-stroke participants and in warmer months (−14.54 [SE 4.1] mmHg, p < 0.05) in patients with stroke. Conclusion: Elderly with andwithout stroke respond to orthostatic stress with a greater drop in blood pressure in the warmer seasons.