Baker's yeast (Saccharomyces cerevisiae) catalyzed synthesis of bioactive heterocycles and some stereoselective reactions

Abstract

Saccharomyces cerevisiae, commonly known as baker's yeast, has gained significant importance as a mild, low-cost, environmentally benign biocatalyst. Initially it was mostly employed as an efficient catalyst for the enantioselective reduction of carbonyl compounds. Over the last decade, baker's yeast has found versatile catalytic applications in various organic transformations. Many multicomponent reactions were also catalyzed by baker's yeast. Various heterocyclic scaffolds with immense biological activities were synthesized by employing baker's yeast as catalyst at room temperature. In this communication, we have summarized baker's yeast catalyzed various organic transformations focusing primarily on heterocyclic synthesis.