Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation

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Abstract

Wogonin and astringin were synthesized from inexpensive chrysin and piceid in short steps. The key feature of these syntheses is site-selective transformation. The target molecules were obtained in 27 and 62% yields from the starting materials, respectively.

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Yamashita, Y., Biard, A., Hanaya, K., Shoji, M., & Sugai, T. (2017). Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation. Bioscience, Biotechnology and Biochemistry, 81(7), 1279–1284. https://doi.org/10.1080/09168451.2017.1303362

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