Simple precision creation of digitally specified, spatially heterogeneous, engineered tissue architectures

Abstract

Complex architectures of integrated circuits are achieved through multiple layer photolithography, which has empowered the semiconductor industry. We adapt this philosophy for tissue engineering with a versatile, scalable, and generalizable microfabrication approach to create engineered tissue architectures composed of digitally specifiable building blocks, each with tuned structural, cellular, and compositional features. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.