The role of stem cells in tumor targeting and growth suppression of gliomas

3Citations
Citations of this article
16Readers
Mendeley users who have this article in their library.

Abstract

Glioma remains the most challenging solid organ tumor to treat successfully. Based on the capacity of stem cells to migrate extensively and target invading glioma cells, the transplantation of stem cells as a cell-based delivery system may provide additional tools for the treatment of gliomas. In addition to the use of modified stem cells for the delivery of therapeutic agents, unmodified stem cells have been shown to have growth-suppressing effects on tumors in vitro and in vivo. This review outlines the probable factors involved in tumor tropism and tumor growth suppression, with a specific focus on the use of unmodified stem cells in the treatment of gliomas. Based on these and further future data, clinical trials may be justified.

Cite

CITATION STYLE

APA

Eskandary, H., Basiri, M., Nematollahi-Mahani, N. S., & Mehravaran, S. (2011, April 4). The role of stem cells in tumor targeting and growth suppression of gliomas. Biologics: Targets and Therapy. Dove Medical Press Ltd. https://doi.org/10.2147/BTT.S17838

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free