Economic Impact Of Adverse Drug Reactions: A Pubmed Based Study

  • Bhat B
  • D S
  • Udupa N
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Abstract

Objectives: To list and analyze cost incurred for the treatment of ADRs from the articles present in pubmed database. Methods: Pubmed database was searched with keywords “Cost incurred due to Adverse Drug Reactions”, “Preventable Adverse Drug Reactions” and “Economic impact of ADR”. Results: A total of 18, 19 and 141 articles were present in pubmed with the key words “Cost incurred due to Adverse Drug Reactions”, “Preventable Adverse Drug Reactions” and “Economic impact of ADR” respectively. Majority of the ADRs were for due to medications used for the treatment of cancer, followed by Disease Modifying Anti-Rheumatoid Drugs. On an average the cost of treatment for each ADR was found to be 2000 USD (in an US set up), 2000 Euro (in an European set up), and around 150 USD for an Indian set up. However, the cost incurred due to ADRs depends on various factors. It was observed from one of the study that out of all ADRs that occurred, 60 percent of the ADRs were preventable. Conclusions: It is evident from this study that ADRs cause unnecessary economic burden to the patients. By taking proper care, training the patient and physician can surely lessen the occurrence of avoidable or preventable ADRs thus may decrease the economic burden on patients. A study can be taken up to understand the economic burden due to ADRs caused by herbal medicines as there are hardly any studies conducted in this domain.

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Bhat, B., D, S., & Udupa, N. (2016). Economic Impact Of Adverse Drug Reactions: A Pubmed Based Study. Value in Health, 19(7), A486–A487. https://doi.org/10.1016/j.jval.2016.09.810

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