Niosome: A Comprehensive Review of Novel Drug Delivery System

Abstract

Non-ionic surfactant vesicles, which make up niosomes, are made by hydrating a mixture of non-ionic surfactant and cholesterol. They can be employed as both lipophilic and amphiphilic drug carriers. Niosomes are a kind of delivery mechanism where drugs are contained within vesicles. Niosomes have a variety of characteristics, including being non-immunogenic, biodegradable, and structurally flexible. The reason for writing this review is to shed light on the several ways that niosomes are utilized to treat a variety of illnesses. We will examine several facets of niosomes in this review paper. These include their manufacture method, mechanism of action, how neosomes aid in drug penetration, how they are used as a permeation enhancer, how they are applied, how they can be used to treat various diseases and their toxicity, and how surfactants can be used to mitigate their toxicity. Keywords: Niosome, Non- Ionic surfactants, Liposomes, Nanocarrires, Charge Inducers.