Abstract
By using the Inverted Chirality Columns Approach (ICCA) we have developed an enantioselective UHPSFC method to determine the enantiomeric excess (ee) of (-)-Δ9-THC in medicinal marijuana (Bedrocan®). The ee was high (99.73%), but the concentration of the (+)-enantiomer (0.135%) was not negligible, and it is worth a systematic evaluation of bioactivity.
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CITATION STYLE
Mazzoccanti, G., Ismail, O. H., D’Acquarica, I., Villani, C., Manzo, C., Wilcox, M., … Gasparrini, F. (2017). Cannabis through the looking glass: Chemo- and enantio-selective separation of phytocannabinoids by enantioselective ultra high performance supercritical fluid chromatography. Chemical Communications, 53(91), 12262–12265. https://doi.org/10.1039/c7cc06999e
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