A Sympathetic View on Fat by Leptin

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Abstract

Zeng et al. reveal that the lipolytic effect of the hormone leptin is mediated by sympathetic nerve fibers that directly "envelope" white adipocytes. Local activation of the sympathetic input to the fat opens new venues to circumvent central leptin resistance in obesity.

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Varela, L., & Horvath, T. L. (2015, September 24). A Sympathetic View on Fat by Leptin. Cell. Cell Press. https://doi.org/10.1016/j.cell.2015.09.016

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