Objectives: To obtain Western European perspectives on the economic burden of atherothrombosis in patients with multiple risk factors only (MRF), cerebrovascular disease (CVD), coronary artery disease (CAD), and in the under-evaluated group of patients with peripheral arterial disease (PAD), we examined vascular-related hospitalisation rates and associated costs in France and Germany. Design: The prospective REACH Registry enrolled 4693 patients in France, and 5594 patients in Germany (from December 2003 until June 2004). Methods: For each country, 2-year rates and costs associated with cardiovascular events and vascular-related hospitalisations were examined for patients with MRF, CVD, CAD, and PAD. Results: Two-year hospitalisation costs were highest for patients with PAD (3182.1€ for France; 2724.4€ for Germany) and lowest for the MRF group (749.1€ for France; 503.3€ for Germany). Peripheral revascularizations and amputations were the greatest contributors to costs for all risk groups. Across all PAD subgroups, peripheral procedures constituted approximately half of the 2-year costs. Conclusion: Hospitalisation rates and costs associated with atherothrombotic disease in France and Germany are high, especially so for patients with PAD. © 2011 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
Smolderen, K. G., Wang, K., De Pouvourville, G., Brüggenjürgen, B., Röther, J., Zeymer, U., … Magnuson, E. A. (2012). Two-year vascular hospitalisation rates and associated costs in patients at risk of atherothrombosis in France and Germany: Highest burden for peripheral arterial disease. European Journal of Vascular and Endovascular Surgery, 43(2), 198–207. https://doi.org/10.1016/j.ejvs.2011.09.016