In this report, an idea of integrating ultrananocrystalline diamond (UNCD) with pyrolytic carbon (PyC)-based mechanical heart valves, has been demonstrated. The report addresses the strategies to avoid graphitization and film delamination during the diamond coating. Raman and scratch tests showed that a UNCD film with high purity could adhere to the PyC substrate strongly. A thrombin generation study demonstrated an excellent biocompatibility of UNCD towards fresh human platelets. These results suggest that UNCD could be a good candidate of surface material for next generation heart valves and other implantable devices.
Zeng, H., Yin, W., Catausan, G., Moldovan, N., & Carlisle, J. (2016). Ultrananocrystalline diamond integration with pyrolytic carbon components of mechanical heart valves. Diamond and Related Materials, 61, 97–101. https://doi.org/10.1016/j.diamond.2015.11.020