Lymphomatoid granulomatosis: Report of a case

Abstract

In 1972 Liebow defined lymphomatoid granulomatosis as an 'angiocentric and angiodestructive lymphoreticular and granulomatous disease involving predominantly the lungs'. Its clinical and radiological manifestations are similar to the limited form of Wegener's granulomatosis, but the cellular infiltrate is atypical and a lymphoma develops in a significant proportion. There are certain affinities with malignant midline reticulosis and immunoblastic lymphadenopathy. Although some 200 cases have been reported from North America and Australia, there are very few in the European literature, three of which are British. This paper reports the fourth British case.