Effect of D-(+)-Glucose on the Stability of Polyvinyl Alcohol Fricke Hydrogel Three-Dimensional Dosimeter for Radiotherapy

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Abstract

D-(+)-glucose (Glc) was added to the original Fricke polyvinyl alcohol-glutaraldehyde-xylenol orange (FPGX) hydrogel dosimeter system to make a more stable FPGX hydrogel three-dimensional dosimeter in this paper. Polyvinyl alcohol was used as a substrate, which was combined with Fricke solution. Various concentrations of Glc were tested with linear relevant fitting for optimal hydrogel production conditions. The effects of various formulations on the stability and sensitivity of dosimeters were evaluated. The results indicated that D-(+)-Glc, as a free radical scavenger, had a great effect on stabilizing the dose response related to absorbency and reducing the auto-oxidization of ferrous ions. A careful doping with Glc could slow down the color change of the dosimeter before and after radiation without any effect on the sensitivity of the dosimeter.

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Yang, Y., Chen, J., Yang, L., Chen, B., Sheng, Z., Luo, W., … Chen, J. (2016). Effect of D-(+)-Glucose on the Stability of Polyvinyl Alcohol Fricke Hydrogel Three-Dimensional Dosimeter for Radiotherapy. Nuclear Engineering and Technology, 48(3), 608–612. https://doi.org/10.1016/j.net.2016.04.005

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