Effect of Zirconium Oxide and Zinc Oxide Nanoparticles on Physicochemical Properties and Antibiofilm Activity of a Calcium Silicate-Based Material

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Abstract

The aim of the present study was to evaluate the antibiofilm activity against Enterococcus faecalis , compressive strength. and radiopacity of Portland cement (PC) added to zirconium oxide (ZrO 2 ), as radiopacifier, with or without nanoparticulated zinc oxide (ZnO). The following experimental materials were evaluated: PC, PC + ZrO 2 , PC + ZrO 2 + ZnO (5%), and PC + ZrO 2 + ZnO (10%). Antibiofilm activity was analyzed by using direct contact test (DCT) on Enterococcus faecalis biofilm, for 5 h or 15 h. The analysis was conducted by using the number of colony-forming units (CFU/mL). The compressive strength was performed in a mechanical testing machine. For the radiopacity tests, the specimens were radiographed together with an aluminium stepwedge. The results were submitted to ANOVA and Tukey tests, with level of significance at 5%. The results showed that all materials presented similar antibiofilm activity ( P>0.05 ). The addition of nanoparticulated ZnO decreased the compressive strength of PC. All materials presented higher radiopacity than pure PC. It can be concluded that the addition of ZrO 2 and ZnO does not interfere with the antibiofilm activity and provides radiopacity to Portland cement. However, the presence of ZnO (5% or 10%) significantly decreased the compressive strength of the materials.

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Guerreiro-Tanomaru, J. M., Trindade-Junior, A., Cesar Costa, B., Da Silva, G. F., Drullis Cifali, L., Basso Bernardi, M. I., & Tanomaru-Filho, M. (2014). Effect of Zirconium Oxide and Zinc Oxide Nanoparticles on Physicochemical Properties and Antibiofilm Activity of a Calcium Silicate-Based Material. Scientific World Journal, 2014. https://doi.org/10.1155/2014/975213

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