Bloodstream infections (BSI) remain a major challenge with high mortality rate, with an incidence that is increasing worldwide. Early treatment with appropriate therapy can reduce BSI-related morbidity and mortality. However, despite recent progress in molecular based assays, complex sample preparation steps have become critical roadblock for a greater expansion of molecular assays. Here, we report a size based, label-free, bacteria separation from whole blood using elasto-inertial microfluidics.
Faridi, M. A., Ramachandraiah, H., Banerjee, I., Ardabili, S., Zelenin, S., & Russom, A. (2017). Elasto-inertial microfluidics for bacteria separation from whole blood for sepsis diagnostics. Journal of Nanobiotechnology, 15(1). https://doi.org/10.1186/s12951-016-0235-4