Electrical storm in Brugada syndrome successfully treated using isoprenaline

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A case of an electrical storm occurring in a patient implanted with a cardioverter-defibrillator for Brugada syndrome is reported. Recurrent ventricular fibrillation was initiated by short-coupled isolated monomorphic ventricular premature beats probably originating from the right ventricular outflow tract, associated with a manifest electrocardiographic pattern of Brugada syndrome. Infusion of atropine accelerated the heart rate but did not prevent ventricular fibrillation, however, low doses of isoprenaline quickly obviated any recurrence of ventricular fibrillation. This was associated with the disappearance of the short-coupled premature beats together with a normalization of the electrocardiographic pattern. Possible mechanisms are discussed according to the accepted pathophysiological hypothesis. © 2004 The European Society of Cardiology. Published by Elsevier Ltd. All rights reserved.




Maury, P., Couderc, P., Delay, M., Boveda, S., & Brugada, J. (2004). Electrical storm in Brugada syndrome successfully treated using isoprenaline. Europace, 6(2), 130–133. https://doi.org/10.1016/j.eupc.2003.11.009

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