Objective Anaesthesia-induced dynamics in EEG are dependent on age and level of anaesthesia, but distinct characterisation in children is incomplete. Here we analyse EEG dynamics in children related to age and level of anaesthesia. Methods Frontal EEG recordings were obtained from 93 children (0–19 years) during routine clinical anaesthesia. EEG segments were selected at four different levels of anaesthesia: emergence, light anaesthesia, deep anaesthesia, and very deep anaesthesia. Results Total power differed significantly over age at deep (R2= 0.314; p < 0.0001) and very deep anaesthesia (R2= 0.403; p < 0.0001). Relative beta band power at light anaesthesia increased linearly with age (R2= 0.239; p < 0.0001). Level of anaesthesia caused significant differences for relative delta band power (increasing with anaesthetic depth), for relative beta band power and for spectral edge frequency (decreasing with anaesthetic depth) for all children (p < 0.0001). Conclusions EEG parameter in children were primary dependent on anaesthetic depth, where beta band power, delta band power and spectral edge frequency showed a linear relation. Age-dependency during anaesthesia procedure were only seen for single EEG parameters. Significance Different levels of anaesthesia can be identified by relative beta band power, relative delta band power and spectral edge frequency irrespective of the children's age.
Koch, S., Stegherr, A. M., Mörgeli, R., Kramer, S., Toubekis, E., Lichtner, G., … Spies, C. (2017). Electroencephalogram dynamics in children during different levels of anaesthetic depth. Clinical Neurophysiology, 128(10), 2014–2021. https://doi.org/10.1016/j.clinph.2017.07.417