Objective: To describe two successful cases of utilizing refrozen blastocysts by vitrification derived from supernumerary embryos. Design: Case report. Setting: Private fertility clinic. Subjects: Two infertility couple. Interventions: Refrozen blastocysts by vitrification derived from supernumerary embryos. Main outcome measures: Obstetric and pediatric results. Results: Two pregnancies obtained from refrozen-warmed blastocysts led to two healthy babies being born without clinical or genetic problems. Conclusion: These case reports support the notion of safely repeating cryopreservation. However, despite these favorable results, there is still a need for prospective controlled studies on the obstetric and neonatal repercussions of refreezing and of vitrification in particular. © 2010 Middle East Fertility Society.
Mauri, A. L., Petersen, C. G., Oliveira, J. B. A., Baruffi, R. L. R., Al-Hasani, S., & Franco, J. G. (2011). Embryos refrozen-thawed by vitrification lead to live births: Case report. Middle East Fertility Society Journal, 16(1), 93–97. https://doi.org/10.1016/j.mefs.2010.09.008