The present review summarizes recent experimental evidences about the existence of the non-cell-autonomous death entosis in physiological and pathophysiological contexts, discusses some aspects of this form of cell death, including morphological, biochemical and signaling pathways that distinguish non-cell-autonomous demises from other death modalities and propose to define this new modality of death as type IV programmed cell death.
Martins, I., Raza, S. Q., Voisin, L., Dakhli, H., Law, F., De Jong, D., … Perfettini, J. L. (2017, June 1). Entosis: The emerging face of non-cell-autonomous type IV programmed death. Biomedical Journal. Elsevier B.V. https://doi.org/10.1016/j.bj.2017.05.001