Erk in Kidney Diseases

  • Feliers D
  • Kasinath B
N/ACitations
Citations of this article
12Readers
Mendeley users who have this article in their library.

Abstract

Acute or chronic kidney injury results from various insults and pathological conditions, and is accompanied by activation of compensatory repair mechanisms. Both insults and repair mechanisms are initiated by circulating factors, whose cellular effects are mediated by activation selective signal transduction pathways. Two main signal transduction pathways are activated during these processes, the phosphatidylinositol 3 ′ kinase (PI-3K)/mammalian target of rapamycin (mTOR) and the mitogen-activated protein kinase (MAPK) cascades. This review will focus on the latter, and more specifically on the role of extracellular signal-regulated kinase (ERK) cascade in kidney injury and repair.

Cite

CITATION STYLE

APA

Feliers, D., & Kasinath, B. S. (2011). Erk in Kidney Diseases. Journal of Signal Transduction, 2011, 1–8. https://doi.org/10.1155/2011/768512

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free