The Escherichia coli ftsK1 mutation attenuates the induction of σS-dependent genes upon transition to stationary phase

3Citations
Citations of this article
14Readers
Mendeley users who have this article in their library.

Abstract

A mutation in the cell division gene ftsK causes super-induction of σ70-dependent stress defense genes, such as uspA, during entry of cells into stationary phase. In contrast, we report here that stationary phase induction of σS-dependent genes, uspB and cfa, is attenuated and that σS accumulates at a lower rate in ftsK1 cells. Ectopic overexpression of rpoS restored induction of the rpoS regulon in the ftsK mutant, as did a deletion in the recA gene. Thus, a mutation in the cell division gene, ftsK, uncouples the otherwise coordinated induction of σS-dependent genes and the universal stress response gene, uspA, during entry into stationary phase. © 2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

Cite

CITATION STYLE

APA

Diez, A. A., Tunlid, A., & Nyström, T. (2002). The Escherichia coli ftsK1 mutation attenuates the induction of σS-dependent genes upon transition to stationary phase. FEMS Microbiology Letters, 206(1), 19–23. https://doi.org/10.1016/S0378-1097(01)00509-2

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free