© 2016 Viviani et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Objectives To estimate the burden of intestinal infectious disease (IID) in the UK and determine whether disease burden estimations using a retrospective study design differ from those using a prospective study design. Design/Setting A retrospective telephone survey undertaken in each of the four countries comprising the United Kingdom. Participants were randomly asked about illness either in the past 7 or 28 days. Participants 14,813 individuals for all of whom we had a legible recording of their agreement to participate Outcomes Self-reported IID, defined as loose stools or clinically significant vomiting lasting less than two weeks, in the absence of a known non-infectious cause. Results The rate of self-reported IID varied substantially depending on whether asked for illness in the previous 7 or 28 days. After standardising for age and sex, and adjusting for the number of interviews completed each month and the relative size of each UK country, the estimated rate of IID in the 7-day recall group was 1,530 cases per 1,000 person-years (95%CI: 1135- 2113), while in the 28-day recall group it was 533 cases per 1,000 person-years (95%CI:377-778). There was no significant variation in rates between the four countries. Rates in this study were also higher than in a related prospective study undertaken at the same time.
Viviani, L., Van Der Es, M., Irvine, L., Tam, C. C., Rodrigues, L. C., Jackson, K. A., … Hunter, P. R. (2016, January 25). Estimating the incidence of acute infectious intestinal disease in the community in the UK: A retrospective telephone survey. PLoS ONE. Public Library of Science. https://doi.org/10.1371/journal.pone.0146171