© 2016 The Author(s).The evolutionarily novel genes originated through different molecular mechanisms are expressed in tumors. Sometimes the expression of evolutionarily novel genes in tumors is highly specific. Moreover positive selection of many human tumor-related genes in primate lineage suggests their involvement in the origin of new functions beneficial to organisms. It is suggested to consider the expression of evolutionarily young or novel genes in tumors as a new biological phenomenon, a phenomenon of TSEEN (tumor specifically expressed, evolutionarily novel) genes.
Kozlov, A. P. (2016, July 19). Expression of evolutionarily novel genes in tumors. Infectious Agents and Cancer. BioMed Central Ltd. https://doi.org/10.1186/s13027-016-0077-6