The effects of monocular deprivation (MD) on the ocular dominance of visual cortical neurons are a paradigmatic example of experience-dependent plasticity. Here we review recent data showing that extracellular matrix (ECM) plays an important role in the control of experience-dependent plasticity both in the developing and adult visual cortex.
Berardi, N., Pizzorusso, T., & Maffei, L. (2004, December 16). Extracellular matrix and visual cortical plasticity: Freeing the synapse. Neuron. Cell Press. https://doi.org/10.1016/j.neuron.2004.12.008