Extra-skeletal plasmablastic myeloma presenting as palatal growth – An unusual entity

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Introduction Multiple myeloma (MM) is characterized by malignant proliferation of plasma cells, monoclonal bone marrow plasmacytosis, the presence of M-protein in serum and/or in urine and osteolytic bone lesions. Presentation of case We report a case of a 28-years old female, who was diagnosed to have relapsing extra-skeletal and extra-nodal plasmablastic myeloma, an atypical variant of MM with a poor prognosis. In addition to bone marrow plasmacytosis and the presence of M protein in the serum, the patient had an extramedullary lesion affecting the hard palate. Discussion There is a strong correlation with age. The peak incidence is seen in 6th-7th decade. The clinical course in adolescents and young individuals is generally indolent and the survival is longer. Extramedullary myelomas are rare tumors accounting for 0.4% of all head and neck malignancies. Conclusion A case of extraskeletal plasmablastic myeloma presenting as a hard palate growth and that too in young female patient is an extremely rare and requires a multidisciplinary approach for management.




Kumar, S., Bhutani, N., Bhargawa, S., Kataria, S. P., & Sen, R. (2017). Extra-skeletal plasmablastic myeloma presenting as palatal growth – An unusual entity. International Journal of Surgery Case Reports, 41, 423–426. https://doi.org/10.1016/j.ijscr.2017.11.023

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