A novel sesterterpenoid, nitiol, as a potent enhancer of IL-2 gene expression in a human T cell line, from the Peruvian folk medicine 'Hercumpuri' (Gentianella nitida)

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Abstract

A novel sesterterpenoid designated as nitiol (1), possessing enhancement activity of IL-2 gene expression in a human T cell line, was isolated from the Peruvian folk medicine 'Hercampuri' (Gentianella nitida). The structure was elucidated by extensive spectroscopic investigation.

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Kawahara, N., Nozawa, M., Kurata, A., Hakamatsuka, T., Sekita, S., & Satake, M. (1999). A novel sesterterpenoid, nitiol, as a potent enhancer of IL-2 gene expression in a human T cell line, from the Peruvian folk medicine “Hercumpuri” (Gentianella nitida). Chemical and Pharmaceutical Bulletin, 47(9), 1344–1345. https://doi.org/10.1248/cpb.47.1344

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