APE1 shRNA‐loaded cancer stem cell‐derived extracellular vesicles reverse Erlotinib resistance in non‐small cell lung cancer via the IL‐6/STAT3 signalling

  • Tang C
  • Qin L
  • Gao Y
  • et al.
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Abstract

Graphical Abstract Collectively, these data indicate that APE1 confers Erlotinib resistance by activating the IL-6/STAT3 signaling, suggesting targeting APE1 as a possible therapeutic target in Erlotinib-resistant NSCLC. Clin. Transl. Med. 2022;12:e876. wileyonlinelibrary.com/journal/ctm2 https://doi.

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Tang, C., Qin, L., Gao, Y., Chen, T., Xu, K., Liu, T., & Ren, T. (2022). APE1 shRNA‐loaded cancer stem cell‐derived extracellular vesicles reverse Erlotinib resistance in non‐small cell lung cancer via the IL‐6/STAT3 signalling. Clinical and Translational Medicine, 12(5). https://doi.org/10.1002/ctm2.876

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