Polycystic ovary syndrome (PCOS) is a complex disease with heterogeneous clinical and anatomical features that were first described in 1721 by Antonio Vallisneri. There is still a lack of consensus regarding the criteria to be used for diagnosis of PCOS. Transvaginal ultrasonography with Doppler studies of the ovarian and pelvic vasculature plays an important role in its diagnosis, but findings must be interpreted in light of the patient's symptoms and laboratory findings. © 2007 Elsevier Masson Srl. All rights reserved.
Speca, S., Napolitano, C., & Tagliaferri, G. (2007). The pathogenetic enigma of polycystic ovary syndrome. Journal of Ultrasound, 10(4), 153–160. https://doi.org/10.1016/j.jus.2007.09.006