A phase II clinical trial to analyze olaparib response in patients with BRCA1 and/or BRCA 2 promoter methylation with advanced breast cancer (GEICAM/2015-06 COMETA-Breast study).

  • De La Haba J
  • Guerrero-Zotano A
  • Perez-Fidalgo J
  • et al.
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Abstract

TPS1114Background: Identification of targeted therapies for advanced triple negative breast cancer (TNBC) remains as an important clinical challenge. TNBC frequently shows BRCA dysfunction and 80% ...

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De La Haba, J., Guerrero-Zotano, A., Perez-Fidalgo, J. A., Gonzalez Santiago, S., Muñoz, M., Andres, R., … Rojo, F. (2018). A phase II clinical trial to analyze olaparib response in patients with BRCA1 and/or BRCA 2 promoter methylation with advanced breast cancer (GEICAM/2015-06 COMETA-Breast study). Journal of Clinical Oncology, 36(15_suppl), TPS1114–TPS1114. https://doi.org/10.1200/jco.2018.36.15_suppl.tps1114

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