Improvement of upper extremity motor control and function after home-based constraint induced therapy in children with unilateral cerebral palsy: Immediate and long-term effects

Abstract

Objective To investigate the long-term effects of home-based constraint induced therapy (CIT) on motor control underlying functional change in children with unilateral cerebral palsy (CP). Design Randomized controlled trial. Setting Home based. Participants Children with unilateral CP (N=45; aged 6-12y) were randomly assigned to receive home-based CIT (n=23) or traditional rehabilitation (TR) (n=22). Interventions Both groups received a 4-week therapist-based intervention at home. The home-based CIT involved intensive functional training of the more affected upper extremity during which the less affected one was restrained. The TR involved functional unimanual and bimanual training. Main Outcome Measures All children underwent kinematic and clinical assessments at baseline, 4 weeks (posttreatment), and 3 and 6 months (follow-up). The reach-to-grasp kinematics were reaction time (RT), normalized movement time, normalized movement unit, peak velocity (PV), maximum grip aperture (MGA), and percentage of movement where MGA occurs. The clinical measures were the Peabody Developmental Motor Scales, Second Edition (PDMS-2), Bruininks-Oseretsky Test of Motor Proficiency (BOTMP), and Functional Independence Measure for children (WeeFIM). Results The home-based CIT group showed a shorter RT (P