First case of Oropouche fever detected in the international border region of the Colombian Amazon: clinical characteristics and molecular diagnosis.

Abstract

We report the first case of Oropouche Fever detected in the border region of Colombia using a multiplex real-time PCR, genetic sequencing and clinical characteristics during the Dengue epidemic in 2019. A total of 175 samples were analyzed, from cases notified to the system epidemiological surveillance such as Dengue. The OROV isolate from Leticia belongs to lineage 2 according to both M and S genome segments Maximum Likelihood analysis, shares a common ancestor with samples obtained in Esmeraldas, Ecuador and Turbaco, Colombia. The patient: a woman resident in the border neighborhood of the municipality of Leticia had the following symptoms: fever, headache, retro-orbital pain and myalgias. This cross-border surveillance can be useful to give an alert about the entry or exit of arboviruses circulation in the region, which are often underreported in public health surveillance systems.