Abstract
An intramolecular steroidal 1,2,4,5-tetraoxane has been synthesised in six steps starting from methyl 3-oxo-7α. 12α-diacetoxy-5β-cholan-24-oate. The synthesised 1,2,4,5-tetraoxane has moderate in vitro antimalarial activity against P. falciparum strains (IC50 (D6) = 0.35 μg/mL: IC50 (W2) = 0.29 μg/mL).
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APA
Opsenica, D., Pocsfalvi, G., Milhous, W. K., & Solajǎ, B. A. (2002). Antimalarial peroxides: The first intramolecular 1,2,4,5-tetraoxane. Journal of the Serbian Chemical Society, 67(7), 465–471. https://doi.org/10.2298/JSC0207465O
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