Abstract
Novel nucleoside analogues of structure 3-5 were synthesized starting from (±)-cis-2-amino-3-cyclopentenylmethanol (1). The chlorine derivative 3 inhibited both HIV-1 and HIV-2 replication in MT-4 cells with IC50 values of 10.67 μM and of 13.79 μM, respectively. © 2006 Pharmaceutical Society of Japan.
Author supplied keywords
Cite
CITATION STYLE
APA
Canoa, P., González-Moa, M. J., Teijeira, M., Terán, C., Uriarte, E., Pannecouque, C., & De Clercq, E. (2006). Synthesis and anti-HIV activity of novel cyclopentenyl nucleoside analogues of 8-azapurine. Chemical and Pharmaceutical Bulletin, 54(10), 1418–1420. https://doi.org/10.1248/cpb.54.1418
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
Already have an account? Sign in
Sign up for free