Synthesis and antifungal efficacy of 1,3,5-triazines

  • Milata V
  • Reinprecht L
  • Kizlink J
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Abstract

1,3,5-triazines with tree identical groups: benzotriazol-1/2-yl, imidazol-1-yl, pyrazolyl-1-yl, 3,5-dimethylpyrazolyl-1-yl, 4,5-diphenylimidazol-1-yl, benzimidazolyl-1-yl, 2-methylbenzimidazolyl-1-yl, or 2-phenylbenzimidazolyl-1-yl were synthesised. Their biological activity against wood-destroying fungi Serpula lacrymans, Coniophora puteana and Trametes versicolor was tested by the impregnated filter paper method. S. lacry-mans occurred as the most sensitive fungus (from the 3 fungi) in the presence of triazines. Triazines having three imidazol or three 4,5-diphenylimidazol groups were a slightly more effective than others. However, their efficacy in comparison with the commercial fungicides Tebuconazole and IPBC was insufficient.

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Milata, V., Reinprecht, L., & Kizlink, J. (2012). Synthesis and antifungal efficacy of 1,3,5-triazines. Acta Chimica Slovaca, 5(1). https://doi.org/10.2478/v10188-012-0015-1

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