Klebsiella pneumoniae mutants were obtained after UV irradiation and negative selection with anticapsular serum. Unencapsulation, rather than expression of a structurally altered capsule, was found in the mutants. The mutant strains showed no alterations in their outer membrane proteins and lipopolysaccharide, and a great similarity with the wild type in the properties tested (serum resistance, antimicrobial sensitivity, and lipopolysaccharide-specific bacteriophage sensitivity), with the exception of a higher cell surface hydrophobicity and resistance to bacteriophage FC3-9.
CITATION STYLE
Benedi, V. J., Ciurana, B., & Tomas, J. M. (1989). Isolation and characterization of Klebsiella pneumoniae unencapsulated mutants. Journal of Clinical Microbiology, 27(1), 82–87. https://doi.org/10.1128/jcm.27.1.82-87.1989
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